Fig. 2

Intraventricular hemorrhage increases ventricular volume as well as the number of ChP GFP(+) cells and soma size of those cells in CX₃CR-1^GFPmice. (A) Examples of T2-weighted MRI scans comparing naïve CX₃CR-1^GFP mice with CX₃CR-1^GFP mice at 24 h post-IVH. Note the ventricular dilation and presence of blood within the ventricle in the IVH model. (B) Quantification of ventricular volume. Values are means ± SD, n = 6 in naive group, n = 7 in IVH group, #p < 0.01 by student t-test. (C) Fluorescence images of GFP(+) cells in the ChP of naïve and 24 h post-IVH mice. Scale bar = 50 μm. (D) The number of GFP(+) cells was calculated as a percentage of total ChP cells. Values are mean ± SD, n = 6 in naive and n = 7 in IVH groups. #p < 0.01 by student t-test. (E) Fluorescence images of GFP(+) cells in the ChP of naïve mice and 24 h post-IVH. The first columns scale bar = 20 μm and fourth column scale bar = 5 μm. (F) Soma sizes of ChP GFP(+) cells were quantified. Values are mean ± SD, n = 6 in naive and n = 7 in IVH groups. #p < 0.01 by student t-test